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Most patients that experienced side effects such as myocardial infarction, sudden cardiac death, stroke, palpitations, and tachycardia had preexisting cardiovascular risk factors.

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Tadalafil or placebo was administered 2 hours after tamsulosin following a minimum of 7 days of tamsulosin dosing. Blood pressure was measured manually at 1, 2, 3, 4,6, 7, 8, 10, 12, and 24 hours after tadalafil or placebo dosing.

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